Preimplantation Genetic Testing For Structural Rearrangements? (PGT-SR)

PGT-SR is a form of genetic testing that is used for people who have a chromosome structural rearrangement, such as a chromosome translocation. 

In some people, part of one chromosome attaches to the end of another, or pieces of chromosomes may break off and be swapped around so although that person has a normal complement of chromosomes their embryos could inherit missing or extra pieces of chromosome. This is known as ‘unbalanced translocation’.

Embryos with unbalanced translocations usually do not implant, miscarry or rarely, result in the birth of a child with severe variations. PGT-SR can detect unbalanced translocations, as well as errors of all other chromosomes in a developing embryo.